Preparation of malonic acid dialkyl ester

  • Inventors:
  • Assignees: Mitsubishi Chem Ind Ltd
  • Publication Date: September 29, 1981
  • Publication Number: JP-S56123944-A

Abstract

PURPOSE: To improve the reaction rate and the selectivity in the preparation of the titled compound by the reaction of a monohalogenoacetic acid alkyl ester with CO and a lower aliphatic alcohol, by adding a monohalogenoacetic acid, etc. to the reaction system prior to the reaction. CONSTITUTION: A malonic acid dialkyl ester is prepared by the reaction of a monohalogenoacetic acid alkyl ester with CO and a lower aliphatic alcohol in the presence of cobalt carbonyl catalyst and a basic substance (e.g. alkali metal carbonate.) In the above process, a monohalogenoacetic acid (e.g. monochloroacetic acid, monobromoacetic acid, etc. pref. the one containing same halogen atom as the raw material), a malonic acid monoalkyl ester, or their salts, are added to the reaction system before reaction. The malonic acid monoalkyl ester is pref. a lower alkyl ester, such as methyl ester, ethyl ester, etc., and pref. the one containing the same alkyl group as the objective compound. COPYRIGHT: (C)1981,JPO&Japio

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    US-4935395-AJune 19, 1990Associated Universities, Inc.Homogeneous catalyst formulations for methanol production